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カタログ番号 | 製品名 | 別名 | ターゲット |
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T64336 | Izilendustat | HIF/HIF Prolyl-Hydroxylase | |
Tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate inhibit of human recombinant EGLN-1 as substrate after 20 mins by mass spectrophotometric analysis. | |||
T0446 | Naphazoline hydrochloride | Albalon,Rhinantin,Naphazoline HCl | Adrenergic Receptor |
Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant. | |||
T61233 | Penehyclidine hydrochloride | Penequinine hydrochloride | NF-κB , AChR |
Penehyclidine hydrochloride (Penequinine hydrochloride) is an M1 and M3 antagonist and activates NF-κB in lung tissue. Penehyclidine hydrochloride inhibits the release of inflammatory factors and shows anticholinergic pr... | |||
T1482 | Ciclopirox | HOE296b | ATPase , Ferroptosis , Antibacterial , Autophagy , Antifungal |
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spect... | |||
T9543 | Syk Inhibitor II hydrochloride | Others | |
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of... | |||
T12848 | SB-657510 | Others , Neurotensin Receptor | |
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting U... | |||
T63006 | DHU-Se1 | ||
DHU-Se1 is a potent anti-inflammatory agent. DHU-Se1 stimulates the release of reactive selenium compounds from macrophages and reduces the expression of cellular inflammatory factors such as iNOS and TNF-α. DHU-Se1 bloc... | |||
T62364 | CSF1R-IN-5 | ||
CSF1R-IN-5 is a potent inhibitor of CSF1R. CSF1R-IN-5 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-5 has the potential to be used in the study of cancer diseases. | |||
T62342 | CSF1R-IN-4 | ||
CSF1R-IN-4 is a potent inhibitor of CSF-1R. CSF1R-IN-4 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-4 has potential for the study of cancer diseases. EGFR-IN-40. | |||
T72102 | Glucocorticoid receptor modulator 1 | ||
Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively re... | |||
T78732 | BO-1 | ||
BO-1, a benzoate ester, exhibits antibacterial properties, effectively inhibiting multidrug-resistant Staphylococcus aureus. It synergizes with antibiotics like Ciprofloxacin, reversing resistance in antibiotic-resistant... | |||
T74799 | NF-κB-IN-8 | NF-κB | |
NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2. Additionally, it inhibits ALP activity and is usable in inflammation research, inclu... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T3887 | Rosarin | Others | |
Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice . | |||
TN4234 | Hydrangenol | NOS , NF-κB , Nrf2 , NO Synthase , Antifection , Autophagy | |
T6S1049 | Wilforine | ATPase | |
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi... | |||
T1611 | Isotretinoin | 13-cis-Retinoic acid | Retinoid Receptor , Endogenous Metabolite , Autophagy |
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall... | |||
T9113 | Myristicin | Myristicine | IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase |
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ... | |||
T3123 | Allicin | ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection | |
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus... | |||
TN5369 | Dehydroleucodine | Dehydroleucodin | |
Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating a... | |||
TN3070 | 4beta-Hydroxywithanolide E | PARP , HSP , NF-κB , COX | |
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPJ-00327 | M-CSF/CSF1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th... | |||
TMPY-02028 | RON/CD136 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ... | |||
TMPJ-00623 | BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc) | Rhesus | HEK293 Cells |
TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules in local and systemic inflammatory network, and the plasma... | |||
TMPK-01165 | MCEMP1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
A cecal ligation and puncture-induced sepsis mouse model was established to determine the expression of mast cell expression membrane protein 1 (MCEMP1). MCEMP1 in T lymphocytes isolated from sepsis mice were up- or down... | |||
TMPK-01137 | FAM3D Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m... | |||
TMPJ-00397 | IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to I... | |||
TMPY-06836 | NR3C1 Protein, Human, Recombinant (His) | Human | E. coli |
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements ... | |||
TMPY-01466 | S100A12 Protein, Human, Recombinant | Human | E. coli |
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that... | |||
TMPY-01879 | S100A14 Protein, Human, Recombinant (His) | Human | E. coli |
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that... | |||
TMPY-04260 | P38 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol... | |||
TMPY-01000 | BVES Protein, Human, Recombinant (GST) | Human | E. coli |
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protecti... | |||
TMPY-01816 | Pentraxin 3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin dom... | |||
TMPY-04391 | Lyn Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many f... | |||
TMPY-04550 | JNK2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm... | |||
TMPY-01926 | S100A10 Protein, Human, Recombinant (His) | Human | E. coli |
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that... |
カタログ番号 | 製品名 | ||
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L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L9000 | Apoptosis Compound Library | 1760 compounds | |
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; |